Confirmation Letters
The table below provides confirmation requests submitted to APHIS and APHIS’ corresponding response. The definitions for the exemption categories in the table are in the Table Key below.
Table Key
(b)(1): A change resulting from cellular repair of a targeted DNA break in the absence of an externally provided repair template
(b)(2): A targeted single base pair substitution
(b)(3): A gene known to occur in the plant’s gene pool, or a change in a targeted sequence to correspond to a known allele of such a gene or to a known structural variation present in the gene pool
(AM1): An indel or contiguous deletion of any size, made at a targeted location, with or without insertion of DNA if generated without using a repair template, or without insertion of DNA if generated using a repair template
(AM2): A plant with up to twelve (12) modifications, made simultaneously or sequentially, if each modification individually qualifies for exemption and occurs in a different gene
(c): A plant-trait-mechanism of action combination that has been previously reviewed for risks to plant health and determined by APHIS not to be regulated under this part, either via the Regulatory Status Review process or a petition submitted pursuant to the legacy part 340 regulations.